diff --git a/README.md b/README.md index 5db6036..02cabbe 100644 --- a/README.md +++ b/README.md @@ -35,14 +35,17 @@ this day. The age-stratified IFR was calculated from three sources: 1. *Total deaths* and *deaths per age bracket* from the [Ministry of Health's daily report for 29 May][daily] (table 2 and table 3) 1. *Population pyramid* for Spain, from [worldpopulationreview.com][wpop] -In order to minimize right-censoring, the parameters *total deaths* and *deaths -per age bracket* should be obtained from a point in time as close as possible -to when the serosurvey was conducted (18 May to 01 June.) We found only two -Ministry of Health reports in this time period that document deaths per age -bracket: [18 May][dailyalt], [29 May][daily]. However the Ministry of Health -has made significant corrections to deaths statistics on 25 May by subtracting -approximately 2 000 deaths. Therefore we trusted the statistics from 29 May over -those of 18 May. +In order to minimize right-censoring (deaths lagging infections,) the +parameters *total deaths* and *deaths per age bracket* should be obtained from +a point in time as close as possible to when the serosurvey was conducted (18 +May to 01 June, preferably closer to the mid-point 25 May.) This is because the +seroconversion time is roughly the same as the time between infection and +death. We found only two Ministry of Health reports in this time period that +document deaths per age bracket: [18 May][dailyalt], [29 May][daily]. However +the Ministry of Health has made significant corrections to deaths statistics on +25 May by subtracting approximately 2 000 deaths. Therefore we trusted the +statistics from 29 May over those of 18 May. Furthermore, 29 May is closer to +the mid-point. Important detail to note: there were 27 121 total deaths, however age information was only available for 20 585 deaths, and was missing for 6 536 deaths.