ENE-COVID is no longer the largest serosurvey
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*Updated: 07 Oct 2020*
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*Updated: 21 Oct 2020*
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Author: Marc Bevand
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Author: Marc Bevand
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@@ -349,7 +349,7 @@ for all regions. For example, in the US the average flu IFR is 0.078%, compared
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# Calculating the age-stratified IFR of COVID-19 from the Spanish ENE-COVID study
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# Calculating the age-stratified IFR of COVID-19 from the Spanish ENE-COVID study
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The largest serological prevalence survey of COVID-19 was conducted by Spain
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One of the largest serological prevalence surveys of COVID-19 was conducted by Spain
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during the second round of the ENE-COVID study that analyzed 63 564 samples between 18 May
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during the second round of the ENE-COVID study that analyzed 63 564 samples between 18 May
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2020 and 01 June 2020. We used its [provisional results][sero] published on 03
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2020 and 01 June 2020. We used its [provisional results][sero] published on 03
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June to calculate the overall and age-stratified IFR of COVID-19 with the
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June to calculate the overall and age-stratified IFR of COVID-19 with the
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@@ -374,8 +374,7 @@ The average IFR for Spain is **1.117%**. However the true IFR may be higher due
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to right-censoring, under-reporting of deaths, or low specificity of the serological test;
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to right-censoring, under-reporting of deaths, or low specificity of the serological test;
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or the true IFR may be lower due to low sensitivity of the serological test.
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or the true IFR may be lower due to low sensitivity of the serological test.
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The Spanish serological study remains the largest published study available to
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The age-stratified IFR was calculated from three sources:
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this day. The age-stratified IFR was calculated from three sources:
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1. Detailed *prevalence data for age brackets*, from the [serosurvey][sero] (table 1)
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1. Detailed *prevalence data for age brackets*, from the [serosurvey][sero] (table 1)
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1. *Total deaths* and *deaths per age bracket* from the [Ministry of Health's daily report for 29 May][daily] (table 2 and table 3)
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1. *Total deaths* and *deaths per age bracket* from the [Ministry of Health's daily report for 29 May][daily] (table 2 and table 3)
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